Niekerkshoop is a town situated along the R386 Regional Route in the Northern Cape Province of South Africa.
Niekerkshoop is located approximately 40 km north of Prieska and 80 km south-west of Griekwastad (also known as Griquatown)
Niekerkshoop is attractively placed between hills, and large trees shade the streets. There is no domestic water supply but irrigation water is supplied by a spring to the north of the town.
Niekerkshoop falls within Siyathemba Local Municipality and Pixley ka Seme District Municipality.
The town was laid out on the farm Modderfontein in 1902 and has been administered by a village management board since 1904. The town was named after the owners of the farm, brothers named Van Niekerk.